RPL13 - ribosomal protein L13 Gene
Also Known as L13; BBC1; D16S44E; SEMDIST; D16S444E
Species: Homo sapiens
About RPL13
This gene has 15 transcripts (splice variants), 244 orthologues and is associated with 2 phenotypes. Ubiquitous expression in ovary (RPKM 234.6), spleen (RPKM 109.8) and 25 other tissues.
Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L13E family of ribosomal proteins. It is located in the cytoplasm. This gene is expressed at significantly higher levels in benign breast lesions than in breast carcinomas. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2011]
RPL13 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_000977.4 | NP_000968.2 | 60S ribosomal protein L13 isoform 1 |
| NM_001243131.1 | NP_001230060.1 | 60S ribosomal protein L13 isoform 3 |
| NM_033251.2 | NP_150254.1 | 60S ribosomal protein L13 isoform 1 |
RPL13 Protein Structure
Ribosomal_L13e: Ribosomal protein L13e (8 - 185)
- 0
- 100
- 200
- 211 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
60S ribosomal protein L13 |
|
RPL13 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | Verweise |
|---|---|---|---|---|---|---|---|
|
Intra
|
RPL13 | P26373 | BRIX1 | Homo sapiens | Q8TDN6 | 33961781 | |
|
Intra
|
RPL13 | P26373 | NCK1 | Homo sapiens | P16333 | 17474147 | |
|
Intra
|
RPL13 | P26373 | HTT | Homo sapiens | P42858 | 32814053 | |
|
Intra
|
RPL13 | P26373 | HTT | Homo sapiens | P42858 | 32814053 | |
|
Intra
|
RPL13 | P26373 | HTT | Homo sapiens | P42858 | 32814053 | |
|
Intra
|
RPL13 | P26373 | TERF2 | Homo sapiens | Q15554 | 21044950 | |
|
Intra
|
RPL13 | P26373 | TERF2 | Homo sapiens | Q15554 | 21044950 | |
|
Intra
|
RPL13 | P26373 | MRPL38 | Homo sapiens | Q96DV4 | 28514442 | |
|
Intra
|
RPL13 | P26373 | PIK3R1 | Homo sapiens | P27986 | 17474147 |
RPL13 Antibodies
| Art. -Nr. | Produktname | Anwendung | Reactivity |
|---|---|---|---|
| HY-P87055 | RPL13 Antibody (YA6748) | WB, ICC/IF, IHC-P, IF-Tissue, FC | Human, Mouse, Rat |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Spondyloepimetaphyseal Dysplasia, Isidor-Toutain Type |
|
|
| Spondyloepimetaphyseal Dysplasia |
|
|
| Myeloid And Lymphoid Neoplasms Associated With Fgfr1 Abnormalities |
|
|
| Postcholecystectomy Syndrome |
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Bos taurus | RPL13 | VGNC | VGNC:34109 |
| Rattus norvegicus | RPL13 | RGD | RGD:621179 |
| Canis familiaris | RPL13 | VGNC | VGNC:53438 |
| Felis catus | RPL13 | VGNC | VGNC:103746 |
| Macaca mulatta | RPL13 | VGNC | VGNC:82227 |
| Mus musculus | RPL13 | MGD | MGI:105922 |
| Others | RPL13 | NCBI |