HO-PEG17-OH
Based on 1 Customer Validation
HO-PEG17-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- Reinheit: 99.70%
- CAS. Nr.: 351342-04-6
- Formel: C34H70O18
- Molecular Weight:766.91
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Speicherung:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biologische Aktivität
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 351342-04-6
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Appearance Oil
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Molecular Weight 766.91
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Formel C34H70O18
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Color White to off-white
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SMILES
OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (130.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (264 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3039 mL | 6.5197 mL | 13.0393 mL | 32.5984 mL |
| 5 mM | 0.2608 mL | 1.3039 mL | 2.6079 mL | 6.5197 mL | |
| 10 mM | 0.1304 mL | 0.6520 mL | 1.3039 mL | 3.2598 mL | |
| 15 mM | 0.0869 mL | 0.4346 mL | 0.8693 mL | 2.1732 mL | |
| 20 mM | 0.0652 mL | 0.3260 mL | 0.6520 mL | 1.6299 mL | |
| 25 mM | 0.0522 mL | 0.2608 mL | 0.5216 mL | 1.3039 mL | |
| 30 mM | 0.0435 mL | 0.2173 mL | 0.4346 mL | 1.0866 mL | |
| 40 mM | 0.0326 mL | 0.1630 mL | 0.3260 mL | 0.8150 mL | |
| 50 mM | 0.0261 mL | 0.1304 mL | 0.2608 mL | 0.6520 mL | |
| 60 mM | 0.0217 mL | 0.1087 mL | 0.2173 mL | 0.5433 mL | |
| 80 mM | 0.0163 mL | 0.0815 mL | 0.1630 mL | 0.4075 mL | |
| 100 mM | 0.0130 mL | 0.0652 mL | 0.1304 mL | 0.3260 mL |