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Art. -Nr.: HY-158751

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Jun9-72-2

Jun9-72-2 is a papain (Plpro) inhibitor of SARS-CoV-2 with an IC₅₀ value of 0.67 μM. Jun9-72-2 has antiviral activity.

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CAS. Nr.: 2657659-42-0
Formel: C₂₀H₂₁NO
Molecular Weight:291.39

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Jun9-72-2 Chemical Structure

CAS. Nr.: 2657659-42-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Bioz

Biologische Aktivität

Beschreibung

Jun9-72-2 is a papain (Plpro) inhibitor of SARS-CoV-2 with an IC₅₀ value of 0.67 μM. Jun9-72-2 has antiviral activity^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
Vero C1008	CC₅₀	23.69 μM Compound: Jun9-72-2	Cytotoxicity against African green monkey Vero E6 cells incubated for 48 hrs by neutral red uptake assay Cytotoxicity against African green monkey Vero E6 cells incubated for 48 hrs by neutral red uptake assay	[PMID: 38065031]

Chemical Information

CAS. Nr. 2657659-42-0
Molecular Weight 291.39
Formel C₂₀H₂₁NO
SMILES

OC(C=C1)=CC=C1CN(C)[C@@H](C2=CC=CC3=C2C=CC=C3)C
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Ma C, et al. Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay. ACS Cent Sci. 2021 Jul 28;7(7):1245-1260. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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