Polyoxyethylene(20) oleyl ether
Based on 1 Customer Validation
Polyoxyethylene(20) oleyl ether (Polyethylene glycol oleyl ether, with an average Mn of 1150) is a non-ionic surfactant. Polyoxyethylene(20) oleyl ether possesses emulsifying and detergent properties and can be used as a functional additive in drug delivery systems, helping to form stable nanoemulsions.
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- CAS. Nr.: 9004-98-2
- Formel: (C2H4O)xC18H36O
- Molecular Weight:1150 (Average)
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Speicherung:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Polyoxyethylene(20) oleyl ether can be used to construct three self-emulsifying drug delivery systems, protecting the model peptide (Tuftsin) from degradation by intestinal enzymes and promoting its absorption[1].
Polyoxyethylene(20) oleyl ether can effectively penetrate lipid membranes, but its solubility is limited. Especially, it has poor solubility in biomimetic membranes rich in cholesterol, and the dissolution process is slow and incomplete[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 9004-98-2
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Appearance <25°C Solid,>30°C Liquid
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Molecular Weight 1150 (Average)
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Formel (C2H4O)xC18H36O
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Color Colorless to off-white
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SMILES
OCCOCCCCCCCC/C=C/CCCCCCCC.[x]
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Synonyms
Polyethylene glycol oleyl ether, average Mn～1150; Polyethylene glycol monooleyl ether, n～20
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Reinheit & Dokumentation
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Data Sheet (262 KB)
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SDS (313 KB)
- English - EN (313 KB)
- Français - FR (313 KB)
- Deutsch - DE (313 KB)
- Norwegian - NO (313 KB)
- Español - ES (313 KB)
- Swedish - SV (313 KB)
- Italian - IT (313 KB)
- Korean - KR (313 KB)
- Portuguese - PT (313 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Postina A, et al. Oral peptide drug delivery: design of SEDDS providing a protective effect against intestinal membrane-bound enzymes. Drug Deliv Transl Res. 2025 Apr 24. [Content Brief]
[2]. Caritá AC, et al. Solubilization of biomimetic lipid mixtures by some commonly used non-ionic detergents. Chem Phys Lipids. 2023 Sep;255:105327. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Polyoxyethylene(20) oleyl ether Related Classifications
HY-W250168A Related Classifications
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