CD30L/CD153
CD153 is the TNF-family ligand for CD30 (TNFRSF8), encoded by the TNFSF8 gene and expressed predominantly on activated T cells, neutrophils, eosinophils and some B cells. As a type II transmembrane protein it can trigger CD30 on the opposing cell, a pathway associated with Th2-type cytokine production, NF-κB activation and survival signals. The CD30-CD153 axis has been studied in Hodgkin lymphoma, anaplastic large-cell lymphoma and inflammatory skin disease, since Reed-Sternberg cells characteristically display abundant surface CD30. Proteolytic shedding releases soluble CD153, which circulates in patients with lymphoproliferative and inflammatory disorders.
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CD30L/CD153 Recombinant Proteins (9)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
