R-87366
R-87366 is a water-soluble human immunodeficiency virus (HIV) protease inhibitor. R-87366 has potent inhibitory for HIV protease with a Ki value of 11 nM. R-87366 can be used for the research of anti-human immunodeficiency virus (HIV).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 144779-91-9
- Formel: C32H39N7O6
- Molecular Weight:617.70
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Ki: 11 nM (HIV protease)[1].
IC90: 0.5 μM (HIV-1IIIB acutely infected cells)[1]
R-87366 has potent inhibitory for human immunodeficiency virus protease with a Ki value of 11 nM[1].
R-87366 has activity for HIV-1IIIB acutely infected cells with an IC90 value of 0.5 μM[1].
R-87366 has moderate water-solubility[1].
R-87366 (0.25 μM; 0.5 μM) also has active in chronically infected Molt-4/HIV-1IIIB cells, and inhibits the proteolytic processing of p55 into p17[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 144779-91-9
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Molecular Weight 617.70
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Formel C32H39N7O6
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SMILES
O=C(N(CCC1)[C@@H]1C(NC(C)(C)C)=O)[C@@H](O)[C@@H](NC([C@H](CC(N)=O)NC(C2=CN=C3C(C=CC=C3)=N2)=O)=O)CC4=CC=CC=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
R-87366 Related Classifications
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