TES-d15
TES-d15 is the deuterium labeled TES (HY-23430). TES is an excellent hydrogen ion buffer. TES has characteristics such as an appropriate dissociation constant, a low metal-binding constant, and high water solubility. TES can be used in the research of mammalian cell culture, viruses, and so on.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 1219794-63-4
- Formel: C6D15NO6S
- Molecular Weight:244.34
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Beschreibung
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Anwendung
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 1219794-63-4
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Unlabeled CAS 7365-44-8
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Molecular Weight 244.34
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Formel C6D15NO6S
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SMILES
O=S(C([2H])([2H])C([2H])([2H])N([2H])C(C([2H])([2H])O[2H])(C([2H])([2H])O[2H])C([2H])([2H])O[2H])(O[2H])=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Somatic Cell Culture
A method of simulating the in vivo environment in vitro to maintain the cell growth, differentation and main functions.
Reinheit & Dokumentation
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. N E Good, et al. Hydrogen ion buffers for biological research. Biochemistry. 1966 Feb;5(2):467-77. [Content Brief]
[3]. A Itagaki, et al. Tes and HEPES buffers in mammalian cell cultures and viral studies: problem of carbon dioxide requirement. Exp Cell Res. 1974 Feb83(2):351-61. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
TES-d15 Related Classifications
HY-23430S Related Classifications
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