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Art. -Nr.: HY-111281

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UK 39671

UK 39671 is a store-operated calcium permeability inhibitor with an IC₅₀ of 10 μM in thymocytes. UK 39671 prevents the acceleration of Mn²⁺ influx in thymocytes with intracellular calcium store depletion.

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CAS. Nr.: 85473-17-2
Formel: C₁₇H₂₂Cl₂N₂O
Molecular Weight:341.28

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

UK 39671 Chemical Structure

CAS. Nr.: 85473-17-2

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
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Bioz

Biologische Aktivität

Beschreibung

In Vitro

UK 39671 (10 μM) potently inhibits store-regulated plasma membrane Ca²⁺/Mn²⁺ permeability in rat thymocytes with an IC₅₀ of 10 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 85473-17-2
Molecular Weight 341.28
Formel C₁₇H₂₂Cl₂N₂O
SMILES

ClC1=CC=C(C(Cl)=C1)C(O)(CN2C=NC=C2)CCCCCC
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Alvarez J, et al. Cytochrome P450 may regulate plasma membrane Ca2+ permeability according to the filling state of the intracellular Ca2+ stores. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 1992 Jan 06;6(2):786-92. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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