Validamine
Validamine competitively inhibits β-glucosidase in a pH-dependent and dose-dependent manner, with an IC50 value of 2.92mM, and the maximum inhibitory ability is at the optimum pH value of this enzyme.
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- CAS. Nr.: 32780-32-8
- Formel: C7H15NO4
- Molecular Weight:177.20
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
IC50 value of 2.92mM[1]
Chemical Information
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CAS. Nr. 32780-32-8
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Molecular Weight 177.20
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Formel C7H15NO4
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SMILES
OC[C@@H]1[C@H]([C@@H]([C@@H](O)[C@@H](N)C1)O)O
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Synonyms
(1R,2S,3S,4S,6R)-4-Amino-6-(hydroxymethyl)cyclohexane-1,2,3-triol
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Structure Classification
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Initial Source
Streptomyces hygroscopicus var. limoneus,
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)