PV1115
PV1115 is a potent and highly selective Chk2 inhibitor with an IC50 of 0.14 nM, 66000 nM, >100000 nM for Chk2, Chk1 and RSK2, respectively. PV1115 is situated within the ATP-binding pocket of Chk2.
For research use only. We do not sell to patients.
- CAS No.: 1093793-10-2
- Formula: C20H19N7O3
- Molecular Weight:405.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 0.14 nM (Chk2), 66000 nM (Chk1) and >100000 nM (RSK2)[1]
Chemical Information
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CAS No. 1093793-10-2
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Molecular Weight 405.41
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Formula C20H19N7O3
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SMILES
O=C(NC1=CC=C(C=C1)/C(C)=N/NC2=NCCN2)C3=CC4=C(C([N+]([O-])=O)=CC=C4)N3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)