ATM Inhibitor-11
ATM Inhibitor-11 (Compound 1) is an inhibitor for ATM with an IC50 of 0.32 nM. ATM Inhibitor-11 inhibits the KAP1 phosphorylation with an IC50 of 0.97 nM. ATM Inhibitor-11 exhibits high exposure in the brain, heart and plasma of ICR mouse. ATM Inhibitor-11 exhibits anti-tumor efficacy in NCI-H441 xenograft mouse model.
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- No. CAS: 2878473-51-7
- Fòrmula: C27H33FN6O2
- Peso molecular:492.59
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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ATM 0.32 nM (IC50) |
Chemical Information
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No. CAS 2878473-51-7
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Peso molecular 492.59
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Fòrmula C27H33FN6O2
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SMILES
O=C1N(C)C2=C(N1C(C)C)C3=C(C=C(C(C4=CC=C(OCCCN5CCN(CC5)C)N=C4)=C3)F)N=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ATM Inhibitor-11 Related Classifications
HY-169310 Related Classifications
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