DSA8
DSA8 is a type II kinase inhibitor with IRE1 RNase modulating activity. DSA8 can be used for the research of cancer, metabolic disease, suah as diabetes.
For research use only. We do not sell to patients.
- CAS No.: 1157857-37-8
- Formula: C35H37N9O2
- Molecular Weight:615.73
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BaF3 | IC50 |
500 nM
Compound: DSA8
|
Antiproliferative activity against mouse BA/F3 cells expressing Bcr-Abl T315I mutant
Antiproliferative activity against mouse BA/F3 cells expressing Bcr-Abl T315I mutant
|
[PMID: 20604564] |
Chemical Information
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CAS No. 1157857-37-8
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Molecular Weight 615.73
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Formula C35H37N9O2
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SMILES
CC1=CC=C(NC(C2=CC=C(CN3CCN(C)CC3)C=C2)=O)C=C1NC4=C(C5=NC=NC(NC6=CC=C(OC)C=C6)=N5)C=CC=N4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)