AV5116
Based on 1 Customer Validation
AV5116 is a cap-dependent endonuclease inhibitor (CENI) that binds to the active site of the cap-dependent endonuclease (CEN) located in the N-terminal domain of the polymerase acidic. AV5116 exhibits potent inhibitory activity against influenza viruses (influenza A, B, and C viruses). AV5116 can be used for the study of influenza virus infections.
For research use only. We do not sell to patients.
- Purity: 99.57%
- CAS No.: 2417851-90-0
- Formula: C22H17F2N3O4S2
- Molecular Weight:489.51
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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MCE Bioactive Compound Library
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Bioactive Compound Library
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High-Throughput Bioactive Compound Library
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Biological Activity
Chemical Information
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CAS No. 2417851-90-0
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Appearance Solid
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Molecular Weight 489.51
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Formula C22H17F2N3O4S2
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Color White to off-white
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SMILES
O=C1C(N(C=C2)N([C@]3([H])C4=C(SCC5=C(F)C(F)=CC=C53)C=CS4)[C@@]6([H])N1CCOC6)=C(O)C2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 25 mg/mL (51.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0429 mL | 10.2143 mL | 20.4286 mL | 51.0715 mL |
| 5 mM | 0.4086 mL | 2.0429 mL | 4.0857 mL | 10.2143 mL | |
| 10 mM | 0.2043 mL | 1.0214 mL | 2.0429 mL | 5.1071 mL | |
| 15 mM | 0.1362 mL | 0.6810 mL | 1.3619 mL | 3.4048 mL | |
| 20 mM | 0.1021 mL | 0.5107 mL | 1.0214 mL | 2.5536 mL | |
| 25 mM | 0.0817 mL | 0.4086 mL | 0.8171 mL | 2.0429 mL | |
| 30 mM | 0.0681 mL | 0.3405 mL | 0.6810 mL | 1.7024 mL | |
| 40 mM | 0.0511 mL | 0.2554 mL | 0.5107 mL | 1.2768 mL | |
| 50 mM | 0.0409 mL | 0.2043 mL | 0.4086 mL | 1.0214 mL |
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