Aβ-IN-8
Aβ-IN-8 (compound 7e) is a potent inhibitor of the Aβ aggregation.
For research use only. We do not sell to patients.
- Formula: C22H16F3N3O3S
- Molecular Weight:459.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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Molecular Weight 459.44
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Formula C22H16F3N3O3S
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SMILES
O=C1C=C(/C=N/C2=NC3=CC=C(OC(F)(F)F)C=C3S2)N(C)C=C1OCC4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Purity & Documentation
References
[1]. Mohammad Hossein Asgarshamsi, et al. Synthesis of Some Benzothiazole Derivatives Based on 3-Hydroxypyridine-4-one and Benzaldehyde and Evaluation of Their β-Amyloid Aggregation Inhibition Using both Experimental Methods and Molecular Dynamic Simulation. Chem Biodivers. 2023 Sep 10:e202301113. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)