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Cat. No.: HY-208744

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BCL6-IN-14

BCL6-IN-14 is a BCL6 inhibitor with a K_d value of 41.1 μM for the BCL6 BTB domain. BCL6-IN-14 inhibits Karpas-422 tumors. BCL6-IN-14 can be used in cancer-related research.

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CAS No.: 2374712-76-0
화학식: C₂₈H₃₀ClN₇O₆
분자량:596.03

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

BCL6-IN-14 Chemical Structure

CAS No.: 2374712-76-0

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

BCL6-IN-14 is a BCL6 inhibitor with a K_d value of 41.1 μM for the BCL6 BTB domain. BCL6-IN-14 inhibits Karpas-422 tumors. BCL6-IN-14 can be used in cancer-related research^[1].

In Vitro

OthersAnti-cancer

Others

BCL6-IN-14 (2-fold serial dilutions; 60 seconds on-chip, 300 seconds off-chip) binds directly to the purified BCL6 BTB domain with a K_d of 41.1 μM^[1].

Anti-cancer

BCL6-IN-14 inhibits the growth of Karpas-422 tumor cells with an IC₅₀ of 10 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2374712-76-0
분자량 596.03
화학식 C₂₈H₃₀ClN₇O₆
SMILES

CCOC1=C(O)C(C(N)=O)=CC(C2=CN(C(N=CN3C)=C2C3=O)CC(NC4=C(Cl)C=NC(N5CCOC[C@@H]5C)=C4)=O)=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Rima AL-AWAR, et al. Inhibitors of the bcl6 btb domain protein-protein interaction and uses thereof. WO2019153080A1. WIPO (PCT). 2019-02-06.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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