ABC-1

ABC-1 is a human cancer cell line derived from pleural effusion and associated with lung adenocarcinoma. The cited peer-reviewed studies document the identity or experimental use of this line and support investigation of pharmacological response and treatment sensitivity, molecular profiling, cell signaling, differentiation or developmental mechanisms. As an in vitro system, the cells permit controlled comparisons across culture conditions, genetic or pharmacological perturbations, and quantitative phenotypic readouts. The disease designation above describes the source tumor or disorder when such an origin is documented; diseases examined experimentally with the line should instead be treated as model applications. Because passage history, culture conditions, and cross-contamination can alter cell-line behavior, studies should report handling conditions and verify identity. The references were selected for direct relevance to this cell line, its characterization, or its demonstrated use^[1][2].