2. PROTAC
  3. PROTAC Linkers
  4. Bis-PEG6-acid

Bis-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Bis-PEG6-acid Chemical Structure

Bis-PEG6-acid Chemical Structure

CAS No. : 119189-70-7

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100 mg USD 36 In-stock
250 mg USD 68 In-stock
1 g USD 181 In-stock
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Based on 1 publication(s) in Google Scholar

Bis-PEG6-acid Related Antibodies

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Description

Bis-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Bis-PEG6-acid Related Antibodies
Molecular Weight

382.40

Formula

C16H30O10
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC(CCOCCOCCOCCOCCOCCOCCC(O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Bis-PEG6-acid Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bis-PEG6-acid119189-70-7PROTAC LinkersPEGPROTAClinkerE3ubiquitinligaseproteinInhibitorinhibitorinhibit

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Bis-PEG6-acid
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HY-120587
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