Blestriarene B
Blestriarene B ((-)-Blestriarene B) a stilbenoid isolated by the guidance of inhibitory effect of tubulin polymerization from the tubers of Bletilla striata (Orchidaceae).
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- CAS No.: 127211-03-4
- Formule: C30H24O6
- Masse moléculaire:480.51
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Help & FAQs
Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | EC50 |
11.2 μM
Compound: Cirrhopetalanthrin
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Cytotoxicity against human A549 cells after 3 days by sulforhodamine B assay
Cytotoxicity against human A549 cells after 3 days by sulforhodamine B assay
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[PMID: 19193043] |
| BV-2 | IC50 |
46.8 μM
Compound: 22
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Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs by Griess assay
Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs by Griess assay
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[PMID: 31415170] |
| HCT-8 | EC50 |
7.3 μM
Compound: Cirrhopetalanthrin
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Cytotoxicity against human HCT8 cells after 3 days by sulforhodamine B assay
Cytotoxicity against human HCT8 cells after 3 days by sulforhodamine B assay
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[PMID: 19193043] |
| MCF7 | EC50 |
12.5 μM
Compound: Cirrhopetalanthrin
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Cytotoxicity against human MCF7 cells after 3 days by sulforhodamine B assay
Cytotoxicity against human MCF7 cells after 3 days by sulforhodamine B assay
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[PMID: 19193043] |
| Neutrophil | IC50 |
0.6 μM
Compound: 28
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Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate preincubated for 5 mins followed by fMLP/CB-induction
Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate preincubated for 5 mins followed by fMLP/CB-induction
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[PMID: 27525452] |
| Neutrophil | IC50 |
0.9 μM
Compound: 28
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Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/cytochalasin B-induced superoxide anion generation by measuring superoxide dismutase-inhibitable reduction of ferricytochrome c preincubated for 5 mins followed by FMLP/cytochal
Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/cytochalasin B-induced superoxide anion generation by measuring superoxide dismutase-inhibitable reduction of ferricytochrome c preincubated for 5 mins followed by FMLP/cytochal
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[PMID: 27525452] |
Chemical Information
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CAS No. 127211-03-4
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Masse moléculaire 480.51
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Formule C30H24O6
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SMILES
OC1=CC=C2C(C=CC3=C(C4=C5CCC6=CC(O)=CC=C6C5=C(OC)C=C4O)C(O)=CC(OC)=C32)=C1
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Synonyms
(-)-Blestriarene B
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Blestriarene B Related Classifications
HY-142013 Related Classifications
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