2. Anti-infection Metabolic Enzyme/Protease
  3. HCV Protease
  4. BMS 605339

BMS 605339 is a linear tetra-peptide α-ketoamide inhibitor of HCV NS3 protease. BMS 605339 can be used in research related to hepatitis C (HCV infection).

For research use only. We do not sell to patients.

BMS 605339

BMS 605339 Chemical Structure

CAS No. : 630417-82-2

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BMS 605339 Related Antibodies

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Description

BMS 605339 is a linear tetra-peptide α-ketoamide inhibitor of HCV NS3 protease. BMS 605339 can be used in research related to hepatitis C (HCV infection)[1].

Cellular Effect
Cell Line Type Value Description References
Huh-7 CC50
> 100 μM
Compound: 35, BMS-605339
Cytotoxicity against human HuH7 cells
Cytotoxicity against human HuH7 cells
[PMID: 24555570]
Huh-7 EC50
12 nM
Compound: 1; BMS-605339
Antiviral activity against HCV genotype 1b Con1 expressing NS3 protease infected in human Huh7.5 cells assessed as reduction in viral RNA replication by luciferase reporter gene assay
Antiviral activity against HCV genotype 1b Con1 expressing NS3 protease infected in human Huh7.5 cells assessed as reduction in viral RNA replication by luciferase reporter gene assay
[PMID: 27564532]
Molecular Weight

713.84

Formula

C35H47N5O9S
CAS No.
SMILES

O=C([C@H]1N(C[C@H](OC2=NC=CC3=C2C=CC(OC)=C3)C1)C([C@H](C(C)(C)C)NC(OC(C)(C)C)=O)=O)N[C@]4([C@H](C=C)C4)C(NS(=O)(C5CC5)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BMS 605339 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BMS 605339630417-82-2BMS605339BMS-605339HCV ProteaseHCV NS3 ProteaseinfectionInhibitorinhibitorinhibit

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