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Cat. No.: HY-12375

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BMS-903452

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BMS-903452 is a potent and selective GPR119 agonist for diabetes research.

For research use only. We do not sell to patients.

Purity: 99.70%
CAS No.: 1339944-47-6
Formula: C₂₁H₁₉Cl₂FN₄O₄S
Molecular Weight:513.37

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

BMS-903452 Chemical Structure

CAS No.: 1339944-47-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Clinical Trial
Chemical Information
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Bioz

Biological Activity

Description

BMS-903452 is a potent and selective GPR119 agonist for diabetes research^[1].

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 1339944-47-6
Appearance Solid
Molecular Weight 513.37
Formula C₂₁H₁₉Cl₂FN₄O₄S
Color White to off-white
SMILES

ClC1=CN=C(N2CCC(OC3=CC(N(C4=CC=C(S(=O)(C)=O)C=C4F)C=C3Cl)=O)CC2)N=C1
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wacker DA, et al. Discovery of 5-chloro-4-((1-(5-chloropyrimidin-2-yl)piperidin-4-yl)oxy)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyridin-2(1H)-one (BMS-903452), an antidiabetic clinical candidate targeting GPR119. J Med Chem. 2014 Sep 25;57(18):7499-508. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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- Clinical Trial
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References

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BMS-903452

High-Throughput Bioactive Compound Library

Biological Activity

Chemical Information

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BMS-903452 Related Classifications

HY-12375 Related Classifications