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Cat. No.: HY-N8513

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Brevicompanine B

Name: Brevicompanine B
Brand: MedChemExpress
SKU: HY-N8513
Price: 473.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Brevicompanine B, a diketopiperazine alkaloid, is an antiplasmodial agent. Brevicompanine B is active against the malaria parasite Plasmodium falciparum 3D7 IC₅₀ of 35 mg/mL.

For research use only. We do not sell to patients.

CAS No.: 215121-47-4
Formula: C₂₂H₂₉N₃O₂
Molecular Weight:367.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Brevicompanine B Chemical Structure

CAS No.: 215121-47-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Brevicompanine B, a diketopiperazine alkaloid, is an antiplasmodial agent. Brevicompanine B is active against the malaria parasite Plasmodium falciparum 3D7 IC₅₀ of 35 mg/mL^[1].

All Parasite Isoforms :

Chemical Information

CAS No. 215121-47-4
Molecular Weight 367.48
Formula C₂₂H₂₉N₃O₂
SMILES

CC(C)([C@]1(C2=CC=CC=C2N3)[C@]3([H])N(C([C@H]4CC(C)C)=O)[C@@](C(N4)=O)([H])C1)C=C
Structure Classification
- Alkaloids
Initial Source
- Microorganisms
Aspergillus janus
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sprogøe K, et, al. Janoxepin and brevicompanine B: antiplasmodial metabolites from the fungus Aspergillus janus. Tetrahedron. Volume 61, Issue 36, 5 September 2005, Pages 8718-8721.

[2]. Du L, et, al. Diketopiperazine alkaloids from a deep ocean sediment derived fungus Penicillium sp. Chem Pharm Bull (Tokyo). [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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