2. Anti-infection
  3. Bacterial
  4. Broquinaldol

Broquinaldol, a brominated quinoline, is a potent antistaphylococcal agent. Broquinaldol is also a Mn(II) ionophore that can be used to synthesize metalloantibiotic.

For research use only. We do not sell to patients.

Broquinaldol

Broquinaldol Chemical Structure

CAS No. : 15599-52-7

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Broquinaldol Related Antibodies

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Description

Broquinaldol, a brominated quinoline, is a potent antistaphylococcal agent. Broquinaldol is also a Mn(II) ionophore that can be used to synthesize metalloantibiotic[1].

In Vitro

Broquinaldol (compound 1) against Staphylococcus aureus and S. epidermidis strains with MIC values of 0.39-1.56 μM. Broquinaldol is capable of clearing established methicillin-resistant S. aureus, with an EC50 value of 2.6 μM, and S. epidermidis (EC50 = 9.2 μM) biofilms in crystal violet assays[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Broquinaldol Related Antibodies
Molecular Weight

316.98

Formula

C10H7Br2NO
CAS No.
SMILES

CC1=NC2=C(C=C1)C(=CC(=C2O)Br)Br
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (315.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1548 mL 15.7739 mL 31.5477 mL
5 mM 0.6310 mL 3.1548 mL 6.3095 mL
View the Complete Stock Solution Preparation Table

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1548 mL 15.7739 mL 31.5477 mL 78.8693 mL
5 mM 0.6310 mL 3.1548 mL 6.3095 mL 15.7739 mL
10 mM 0.3155 mL 1.5774 mL 3.1548 mL 7.8869 mL
15 mM 0.2103 mL 1.0516 mL 2.1032 mL 5.2580 mL
20 mM 0.1577 mL 0.7887 mL 1.5774 mL 3.9435 mL
25 mM 0.1262 mL 0.6310 mL 1.2619 mL 3.1548 mL
30 mM 0.1052 mL 0.5258 mL 1.0516 mL 2.6290 mL
40 mM 0.0789 mL 0.3943 mL 0.7887 mL 1.9717 mL
50 mM 0.0631 mL 0.3155 mL 0.6310 mL 1.5774 mL
60 mM 0.0526 mL 0.2629 mL 0.5258 mL 1.3145 mL
80 mM 0.0394 mL 0.1972 mL 0.3943 mL 0.9859 mL
100 mM 0.0315 mL 0.1577 mL 0.3155 mL 0.7887 mL
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Broquinaldol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Broquinaldol15599-52-7Bacterialantibacterial agentMn(II) ionophoreantistaphylococcal agentInhibitorinhibitorinhibit

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