c-Met-IN-30
c-Met-IN-30 is a c-MET inhibitor. c-Met-IN-30 inhibits the proliferation of non-small cell lung cancer, pancreatic ductal adenocarcinoma and triple-negative breast adenocarcinoma, and can be used in the research of the above-mentioned cancers.
For research use only. We do not sell to patients.
- Formula: C24H17FN6O2
- Molecular Weight:440.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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c-Met |
c-Met-IN-30 (Compound E22) (72 h) potently inhibits proliferation of EBC-1, SUIT-2, and MDA-MB-231 cancer cells with IC50 values of 0.071 μM, 0.011 μM, and 2.9 μM respectively, while being less active against non-malignant NIH-3T3 cells (IC50 = 1.2 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 440.43
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Formula C24H17FN6O2
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SMILES
FC1=CC(/C(C(N2)=O)=N/NC(N=N3)=NC=C3C4=CC=C(OCC5=CC=CC=C5)C=C4)=C2C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
c-Met-IN-30 Related Classifications
HY-184305 Related Classifications
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