C5aR2 agonist P32
Based on 1 Customer Validation
C5aR2 agonist P32 (Ac-RHYPYWR-OH) is a C5aR2-selective agonist. C5aR2 agonist P32 has been shown to elicit multiple immunomodulatory activities, both by down-regulating the C5aR1-mediated cell signalling, and acting in a C5aR1-independent fashion, in vitro and in vivo.
For research use only. We do not sell to patients.
- Purity: 99.17%
- CAS No.: 2097449-46-0
- Formula: C54H70N16O11
- Molecular Weight:1119.23
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Immunology/Inflammation Compound Library
HY-L007
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Peptide Library
HY-L105
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Protein-protein Interaction Inhibitor Library
HY-L109
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Autoimmune Disease Compound Library
HY-L156
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HY-L159
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HY-L181
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Peptide Compound Library
HY-L105S
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
Complement C5a receptor 2 (C5aR2)[1]
Chemical Information
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CAS No. 2097449-46-0
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Appearance Solid
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Molecular Weight 1119.23
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Formula C54H70N16O11
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Color White to off-white
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SMILES
O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CC2=CC=C(C=C2)O)C(N3[C@@H](CCC3)C(N[C@@H](CC4=CC=C(C=C4)O)C(N[C@@H](CC5=CNC6=CC=CC=C56)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)C
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Sequence
Ac-Arg-His-Tyr-Pro-Tyr-Trp-Arg
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Sequence Shortening
Ac-RHYPYWR
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (89.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8935 mL | 4.4674 mL | 8.9347 mL | 22.3368 mL |
| 5 mM | 0.1787 mL | 0.8935 mL | 1.7869 mL | 4.4674 mL | |
| 10 mM | 0.0893 mL | 0.4467 mL | 0.8935 mL | 2.2337 mL | |
| 15 mM | 0.0596 mL | 0.2978 mL | 0.5956 mL | 1.4891 mL | |
| 20 mM | 0.0447 mL | 0.2234 mL | 0.4467 mL | 1.1168 mL | |
| 25 mM | 0.0357 mL | 0.1787 mL | 0.3574 mL | 0.8935 mL | |
| 30 mM | 0.0298 mL | 0.1489 mL | 0.2978 mL | 0.7446 mL | |
| 40 mM | 0.0223 mL | 0.1117 mL | 0.2234 mL | 0.5584 mL | |
| 50 mM | 0.0179 mL | 0.0893 mL | 0.1787 mL | 0.4467 mL | |
| 60 mM | 0.0149 mL | 0.0745 mL | 0.1489 mL | 0.3723 mL | |
| 80 mM | 0.0112 mL | 0.0558 mL | 0.1117 mL | 0.2792 mL |
C5aR2 agonist P32 Related Classifications
HY-P10639 Related Classifications
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