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Cat. No.: HY-106157R

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Donitriptan (Standard)

(Synonyms: F-11356 free base (Standard))

Donitriptan (Standard) is the analytical standard of Donitriptan (HY-106157). This product is intended for research and analytical applications. Donitriptan is a potent, high efficacy agonist at 5-HT1B/1D receptors with pK_is of 9.4 and 9.3, respectively.

For research use only. We do not sell to patients.

CAS No.: 170912-52-4
Formula: C₂₃H₂₅N₅O₂
Molecular Weight:403.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Donitriptan (Standard) Chemical Structure

CAS No.: 170912-52-4

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Chemical Information
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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 170912-52-4
Molecular Weight 403.48
Formula C₂₃H₂₅N₅O₂
SMILES

NCCC1=CNC2=C1C=C(OCC(N3CCN(C4=CC=C(C#N)C=C4)CC3)=O)C=C2
Synonyms

F-11356 free base (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Muñoz-Islas E, et al. Donitriptan, but not sumatriptan, inhibits capsaicin-induced canine external carotid vasodilatation via 5-HT1B rather than 5-HT1D receptors. Br J Pharmacol. 2006 Sep;149(1):82-91. [Content Brief]

Calculators

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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