RASSF7 - Ras association domain family member 7 Gene

Also Known as HRC1; FAP88; HRAS1; CFAP88; C11orf13

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 8045

About RASSF7

Cytogenetic location: 11p15.5 Genomic coordinates (GRCh38): 11:560,970-564,025 (from NCBI)

This gene has 8 transcripts (splice variants), 1 gene allele, 263 orthologues and 3 paralogues. Broad expression in stomach (RPKM 14.8), colon (RPKM 12.6) and 23 other tissues.

Summary

Predicted to be involved in apoptotic process; regulation of microtubule Cytoskeleton organization; and signal transduction. Located in centriolar satellite. [provided by Alliance of Genome Resources, Apr 2022]

RASSF7 Products (3)

mRNA Protein Name
NM_001143993.2 NP_001137465.1 ras association domain-containing protein 7 isoform 2
NM_001143994.2 NP_001137466.1 ras association domain-containing protein 7 isoform 3
NM_003475.4 NP_003466.1 ras association domain-containing protein 7 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21988832 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RASSF7 Protein Structure

RA

RA: Ras association (RalGDS/AF-6) domain (9 - 87)

  • 0
  • 100
  • 200
  • 300
  • 373 a.a.
Protein Preferred Names Protein Names

ras association domain-containing protein 7

  • HRAS1-related cluster protein 1

RASSF7 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RASSF7 Q02833 SNAP29 Homo sapiens O95721
Anti Tag CoIP
33961781
Intra
RASSF7 Q02833 SNAP29 Homo sapiens O95721
Anti Tag CoIP
24366813
Intra
RASSF7 Q02833 NCK2 Homo sapiens O43639
Y2H Array
31515488
Intra
RASSF7 Q02833 NCK2 Homo sapiens O43639
Validated Y2H
25416956
Intra
RASSF7 Q02833 NCK2 Homo sapiens O43639
Y2H Array
25416956
Intra
RASSF7 Q02833 NCK2 Homo sapiens O43639
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11707 RASSF7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus RASSF7 VGNC VGNC:64510
Rattus norvegicus RASSF7 RGD RGD:1306244
Canis familiaris RASSF7 VGNC VGNC:45384
Mus musculus RASSF7 MGD MGI:1914235
Bos taurus RASSF7 VGNC VGNC:33763
Macaca mulatta RASSF7 VGNC VGNC:76472
Others RASSF7 NCBI