Mesulergine
Mesulergine is an active compound.
For research use only. We do not sell to patients.
- CAS No.: 64795-35-3
- Formula: C18H26N4O2S
- Molecular Weight:362.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Size
Price
Stock
Quantity
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Mesulergine is an active compound.
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO-K1 | IC50 |
120 nM
Compound: Mesulergine
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Antagonist activity at human recombinant 5HT7 receptor expressed in CHOK1 cells assessed as inhibition of serotonon-induced increase in cAMP levels by HTRF assay relative to untreated control
Antagonist activity at human recombinant 5HT7 receptor expressed in CHOK1 cells assessed as inhibition of serotonon-induced increase in cAMP levels by HTRF assay relative to untreated control
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[PMID: 19326916] |
| HEK293 | IC50 |
0.29 μM
Compound: Mesulergine
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Antagonist activity at human 5-HT7 expressed in HEK-293 cells assessed as inhibition in serotonin-induced increase in cAMP level after 45 mins by HTRF assay
Antagonist activity at human 5-HT7 expressed in HEK-293 cells assessed as inhibition in serotonin-induced increase in cAMP level after 45 mins by HTRF assay
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[PMID: 25073094] |
Chemical Information
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CAS No. 64795-35-3
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Molecular Weight 362.49
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Formula C18H26N4O2S
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SMILES
O=S(N[C@@H](C[C@@]12[H])CN(C)[C@]1([H])CC3=CN(C)C4=C3C2=CC=C4)(N(C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Select Batch:
Purity:
99.98%
Assay:
99.98%
ee.:
99.98%
References
Calculators
Molarity Calculator
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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Dilution Calculator
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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