RNA binder 4
RNA binder 4 is an RNA-binding agent that can be used for the synthesis of MJ-NR-27 (HY-183980). MJ-NR-27 is a bifunctional ribonuclease-targeting chimera (RIBOTAC) small molecule that targets NRAS mRNA containing a G-quadruplex structure, and it can be used in cancer research.
For research use only. We do not sell to patients.
- Formula: C23H25N7O
- Molecular Weight:415.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
RNA binder 4 (compound B2) is an RNA-binding agent that can be used for the synthesis of RIBOTAC MJ-NR-27 (HY-183980). MJ-NR-27 targets NRAS mRNA containing a G-quadruplex structure. MJ-NR-27 achieves target RNA degradation by recruiting ribonuclease RNase L, and significantly induces morphological changes in tumor cells. MJ-NR-27 can be used in cancer research[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 415.49
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Formula C23H25N7O
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SMILES
CC1=CC=C(C=C1)C2=NN=C(O2)C3=NC4=C(C=CC=C4)C(NCCN5CCNCC5)=N3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)