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Cat. No.: HY-N8261

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Amicoumacin B

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Amicoumacin B can be produced by actinomycete, strain 04-5195^T.. Amicoumacin B increases the expression of bone morphogenetic protein 2 (BMP-2). Amicoumacin B has inhibitory effect against C. violaceum (MIC = 250 µg/mL). Amicoumacin B has quorum sensing inhibitory activity, and reduces the expression of the C. violaceum operons vioA, vioB, vioD, and vioE, but increases the expression of vioC.

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Pureté: 98.8%
CAS No.: 77674-99-8
Formule: C₂₀H₂₈N₂O₈
Masse moléculaire:424.44

Stockage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Amicoumacin B Chemical Structure

CAS No.: 77674-99-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Voir tous les produits spécifiques à Isoform TGF-beta/Smad :

Smad1
Smad3

Chemical Information

CAS No. 77674-99-8
Appearance Solid
Masse moléculaire 424.44
Formule C₂₀H₂₈N₂O₈
Color White to off-white
SMILES

O=C1C2=C(O)C=CC=C2C[C@@](O1)([H])[C@H](CC(C)C)NC([C@@H](O)[C@@H](O)[C@@H](N)CC(O)=O)=O
Structure Classification
- Antibiotics
Initial Source
- Microorganisms
Nocardia jinanensis sp.
Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (271 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Shi WP, et al. Amicoumacins from a desert bacterium: quorum sensing inhibitor against Chromobacterium violaceum. Nat Prod Res. 2021 Dec;35(23):5508-5512. [Content Brief]

[2]. Sun W, et al. Nocardia jinanensis sp. nov., an amicoumacin B-producing actinomycete. Int J Syst Evol Microbiol. 2009 Feb;59(Pt 2):417-20. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Amicoumacin B

Voir tous les produits spécifiques à Isoform TGF-beta/Smad

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Amicoumacin B Related Classifications

HY-N8261 Related Classifications