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Cat. No.: HY-16088

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BAY 74-4113

BAY 74-4113 is a DGAT1 inhibitor (IC₅₀: 72 nM). BAY 74-4113 can be used in obesity research.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 791593-56-1
Formule: C₂₆H₂₀F₂N₂O₃S
Masse moléculaire:478.51

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

BAY 74-4113 Chemical Structure

CAS No.: 791593-56-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

BAY 74-4113 is a DGAT1 inhibitor (IC₅₀: 72 nM). BAY 74-4113 can be used in obesity research^[1]^[2].

Voir tous les produits spécifiques à Isoform Acyltransferase :

Cellular Effect

Cell Line	Type	Value	Description	References
Sf9	IC₅₀	73 nM Compound: 3, BAY-744113	Inhibition of human DGAT1 expressed in Sf9 cells assessed as formation of didecanoylglycerol product after 1 hr using 14C-decanoyl-CoA by beta scintillation counter Inhibition of human DGAT1 expressed in Sf9 cells assessed as formation of didecanoylglycerol product after 1 hr using 14C-decanoyl-CoA by beta scintillation counter	[PMID: 21868220]

Chemical Information

CAS No. 791593-56-1
Masse moléculaire 478.51
Formule C₂₆H₂₀F₂N₂O₃S
SMILES

FC1=CC=C2C(SC(NC3=C(C=C(C4=CC=C(C=C4)C([C@H]5[C@@H](CCC5)C(O)=O)=O)C=C3)F)=N2)=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Roger Smith, et al. Preparation and use of aryl alkyl acid derivatives for the treatment of obesity. US7091228B2. Bayer Pharmaceuticals Corp. 2004-05-06.

[2]. Kandre S, et al. Synthesis and evaluation of cyclohexane carboxylic acid head group containing isoxazole and thiazole analogs as DGAT1 inhibitors. Eur J Med Chem. 2014 May 22;79:203-15. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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