BR111
BR111 is a C3a protein receptor ligand (pKi = 6.3 nM and Ki = 544 nM).
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- CAS No.: 1037092-93-5
- Formule: C24H26N4O3S
- Masse moléculaire:450.55
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| LAD2 | IC50 |
4 nM
Compound: 10a; BR111
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Antagonist at C3a receptor in human LAD2 cells assessed as inhibition of C3a-induced beta-hexosaminidase release preincubated for 30 mins followed by C3a addition
Antagonist at C3a receptor in human LAD2 cells assessed as inhibition of C3a-induced beta-hexosaminidase release preincubated for 30 mins followed by C3a addition
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[PMID: 31910011] |
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1037092-93-5
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Masse moléculaire 450.55
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Formule C24H26N4O3S
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SMILES
N=C(N)NCCC[C@@H](C(O)=O)NC(C1=CC=C(C(C2=CC=CC=C2)C3=CC=CC=C3)S1)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BR111 Related Classifications
HY-119051 Related Classifications
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