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Cat. No.: HY-178233

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CAT335

CAT335 is a TREK activator. CAT335 selectively and irreversibly activates TREK-1^CG∗. CAT335 can be used in the research of pain sensation, sleep, and intraocular pressure.

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CAS No.: 3032789-44-6
Formule: C₁₈H₁₂Cl₂N₂O₃
Masse moléculaire:375.21

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

CAT335 Chemical Structure

CAS No.: 3032789-44-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

CAT335 is a TREK activator. CAT335 selectively and irreversibly activates TREK-1^CG∗. CAT335 can be used in the research of pain sensation, sleep, and intraocular pressure^[1].

Chemical Information

CAS No. 3032789-44-6
Masse moléculaire 375.21
Formule C₁₈H₁₂Cl₂N₂O₃
SMILES

O=C1C=CC(N1C2=CC=C(C(NCC3=CC=C(C=C3Cl)Cl)=O)C=C2)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Adam R. RENSLO, et al. Covalent, chemogenetic activators for k2p potassium channels and uses thereof. WO2024064923A2. WIPO (PCT). 2023-09-22.

[2]. Deal PE, et al. Development of covalent chemogenetic K2P channel activators. Cell Chem Biol. 2024 Jul 18;31(7):1305-1323.e9. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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