Clofibride
Clofibride is an orally active hypolipaemic agent of pchlorophenoxyisobutyric type. Clofibride has weak toxicity and marked hypocholesterolaemic and hypotriglyceridaemic activity. Clofibride is converted into 4-chlorophenoxyisobutyric acid (CPIB) and 4-hydroxy-N-dimethylbutyramide (HMB) in vivo.
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- CAS No.: 26717-47-5
- Formule: C16H22ClNO4
- Masse moléculaire:327.80
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male CD rats, male and female beagles, olive baboon monkeys[1]
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Dosage:400, 1000 mg/kg (rats); 500 mg/kg (dogs and monkeys)
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Administration:oral, single
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Result:HMB is rapidly metabolized and the half-life of CPIB, the main active metabolite, in the serum is about 12 h in the rat, 43 +9 h in the dog and 6t 1 h in the baboon.
Chemical Information
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CAS No. 26717-47-5
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Masse moléculaire 327.80
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Formule C16H22ClNO4
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SMILES
CC(OC1=CC=C(C=C1)Cl)(C(OCCCC(N(C)C)=O)=O)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Clofibride Related Classifications
HY-119524 Related Classifications
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