Duocarmycin analog-2
Duocarmycin analog-2 is a potent DNA alkylating agent. Duocarmycin analog-2 can be used of synthetic immunoconjugate. Duocarmycin analog-2 has antitumor activity.
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- CAS No.: 1164275-01-7
- Formule: C29H23ClN4O3
- Masse moléculaire:510.97
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
Duocarmycin analog-2 (72 h) has anti-proliferative activity with IC50 values of 0.001, 0.002, 0.002, 0.004, 0.009, 0.01, 0.015, 0.019, 0.019, 0.019, 0.02, 0.04, and 0.068 nM for DU4475, SET2, HCT 16, A2780, MDA MB468, LNCaP, LS174T, CCRF-CEM, COLO205, H2087, H661, A549, and MCD MB231 cells, respectively.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1164275-01-7
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Masse moléculaire 510.97
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Formule C29H23ClN4O3
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SMILES
ClC[C@H]1C2=C(C=C(C3=CC=CC=C32)O)N(C1)C(C4=CC5=CC(NC(C6=CC=C(C=C6)N)=O)=CC=C5N4)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Duocarmycin analog-2 Related Classifications
HY-148091 Related Classifications
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