Fenarimol
Based on 1 Customer Validation
Fenarimol (EL 222) is a potent and orally active fungicide. Fenarimol also is a androgen receptor inhibitor with an IC50 value of 19 µM. Fenarimol decreases the mRNA expression of PBP C3, ODC, IGF-1.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 99.78%
- CAS No.: 60168-88-9
- Formule: C17H12Cl2N2O
- Masse moléculaire:331.20
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| L6 | IC50 |
0.35 μM
Compound: 1
|
Antitrypanosomal activity against trypomastigotes of Trypanosoma cruzi Tulahuen expressing the beta- galactosidase gene infected rat L6 cells after 96 hrs
Antitrypanosomal activity against trypomastigotes of Trypanosoma cruzi Tulahuen expressing the beta- galactosidase gene infected rat L6 cells after 96 hrs
|
[PMID: 22536986] |
| L6 | IC50 |
76.8 μM
Compound: 1
|
Cytotoxicity against rat L6 cells after 72 hrs by Alamar Blue assay
Cytotoxicity against rat L6 cells after 72 hrs by Alamar Blue assay
|
[PMID: 22536986] |
Chemical Information
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CAS No. 60168-88-9
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Appearance Solid
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Masse moléculaire 331.20
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Formule C17H12Cl2N2O
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Color Off-white to light yellow
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SMILES
ClC1=CC=C(C(C2=CN=CN=C2)(C3=C(Cl)C=CC=C3)O)C=C1
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Synonyms
EL 222
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 10 mg/mL (30.19 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (273 KB)
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SDS (623 KB)
- English - EN (623 KB)
- Français - FR (623 KB)
- Deutsch - DE (623 KB)
- Norwegian - NO (623 KB)
- Español - ES (623 KB)
- Swedish - SV (623 KB)
- Italian - IT (623 KB)
- Korean - KR (623 KB)
- Portuguese - PT (623 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0193 mL | 15.0966 mL | 30.1932 mL | 75.4831 mL |
| 5 mM | 0.6039 mL | 3.0193 mL | 6.0386 mL | 15.0966 mL | |
| 10 mM | 0.3019 mL | 1.5097 mL | 3.0193 mL | 7.5483 mL | |
| 15 mM | 0.2013 mL | 1.0064 mL | 2.0129 mL | 5.0322 mL | |
| 20 mM | 0.1510 mL | 0.7548 mL | 1.5097 mL | 3.7742 mL | |
| 25 mM | 0.1208 mL | 0.6039 mL | 1.2077 mL | 3.0193 mL | |
| 30 mM | 0.1006 mL | 0.5032 mL | 1.0064 mL | 2.5161 mL |