RRP1 - ribosomal RNA processing 1 Gene

Also Known as NNP-1; NOP52; RRP1A; D21S2056E

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 8568

About RRP1

Cytogenetic location: 21q22.3 Genomic coordinates (GRCh38): 21:43,789,577-43,805,293 (from NCBI)

This gene has 7 transcripts (splice variants), 195 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 8.5), testis (RPKM 8.1) and 25 other tissues.

Summary

The protein encoded by this gene is the putative homolog of the yeast ribosomal RNA processing protein RRP1. The encoded protein is involved in the late stages of nucleologenesis at the end of Mitosis, and may be required for the generation of 28S rRNA. [provided by RefSeq, Jul 2008]

RRP1 Products (1)

mRNA Protein Name
NM_003683.6 NP_003674.1 ribosomal RNA processing protein 1 homolog A

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
20926688 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RRP1 Protein Structure

Nop52

Nop52: Nucleolar protein,Nop52 (10 - 221)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 461 a.a.
Protein Preferred Names Protein Names

ribosomal RNA processing protein 1 homolog A

  • Nnp1 homolog, nucleolar protein

RRP1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
RRP1 P56182 SPANXN2 Homo sapiens Q5MJ10
Validated Y2H
32296183
Intra
RRP1 P56182 RRP1B Homo sapiens Q14684
Anti Tag CoIP
20926688
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS12289 RRP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12291 RRP1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19949 Rrp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26451 Rrp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus RRP1 VGNC VGNC:34168
Rattus norvegicus RRP1 RGD RGD:1307286
Mus musculus RRP1 MGD MGI:1203500
Felis catus RRP1 VGNC VGNC:64778
Canis familiaris RRP1 VGNC VGNC:45763
Macaca mulatta RRP1 VGNC VGNC:77050
Others RRP1 NCBI