LY6D - lymphocyte antigen 6 family member D Gene

Also Known as E48; Ly-6D

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 8581

About LY6D

Cytogenetic location: 8q24.3 Genomic coordinates (GRCh38): 8:142,784,882-142,786,539 (from NCBI)

This gene has 4 transcripts (splice variants), 90 orthologues and 1 paralogue. Biased expression in esophagus (RPKM 212.7) and skin (RPKM 206.5).

Summary

Predicted to be involved in lymphocyte differentiation. Predicted to act upstream of or within response to stilbenoid. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in cell surface. [provided by Alliance of Genome Resources, Apr 2022]

LY6D Products (1)

mRNA Protein Name
NM_003695.3 NP_003686.1 lymphocyte antigen 6D precursor

LY6D Protein Structure

UPAR_LY6

UPAR_LY6: u-PAR/Ly-6 domain (23 - 93)

  • 0
  • 100
  • 128 a.a.
Protein Preferred Names Protein Names

lymphocyte antigen 6D

  • e48 antigen

LY6D Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
LY6D Q14210 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra
LY6D Q14210 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra
LY6D Q14210 ELOVL4 Homo sapiens Q9GZR5
Y2H Prey Pooling
32296183
Intra
LY6D Q14210 ELOVL4 Homo sapiens Q9GZR5
Validated Y2H
32296183
Intra
LY6D Q14210 ELOVL4 Homo sapiens Q9GZR5
Y2H Array
32296183
Intra
LY6D Q14210 TMEM86B Homo sapiens Q8N661
Validated Y2H
32296183
Intra
LY6D Q14210 TMEM86B Homo sapiens Q8N661
Y2H Array
32296183
Intra
LY6D Q14210 TMEM86B Homo sapiens Q8N661
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Inflammatory Bowel Disease 27

  • IBD27
Squamous Cell Carcinoma, Head And Neck

  • Squamous Cell Carcinoma Of The Head And Neck

  • HNSCC

  • Head And Neck Squamous Cell Carcinoma

  • Squamous Cell Carcinoma Of Lip

  • Squamous Cell Carcinoma, Head And Neck, Somatic

  • Carcinoma Of The Head And Neck

  • Squamous Cell Carcinomas Of Head And Neck

  • Scchn

  • Squamous Cell Carcinoma Of The Hypopharynx

  • Squamous Cell Carcinoma Of The Oropharynx

  • Squamous Cell Carcinoma Of Salivary Glands

  • Squamous Cell Carcinoma Of The Nasal Cavity And Paranasal Sinuses

  • Squamous Cell Carcinoma Of The Nasal Cavity And Sinuses

  • Squamous Cell Carcinoma Of The Oral Cavity

  • Squamous Cell Carcinoma Of The Lip

  • Carcinoma, Squamous Cell Of Head And Neck

  • Lip Squamous Cell Carcinoma

  • Carcinoma, Squamous Cell, Head And Neck

  • Salivary Gland Squamous Cell Carcinoma

  • Cancer Of Head And Neck

  • Squamous Cell Carcinoma Of Oropharynx Nos
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS07896 LY6D Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07899 LY6G6D Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19915 Ly6d Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26283 Ly6g6d Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26416 Ly6d Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris LY6D VGNC VGNC:42872
Bos taurus LY6D VGNC VGNC:31088
Rattus norvegicus LY6D RGD RGD:1306132
Mus musculus LY6D MGD MGI:96881
Macaca mulatta LY6D VGNC VGNC:104461
Others LY6D NCBI