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Cat. No.: HY-119968

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Granaticin

Name: Granaticin
Brand: MedChemExpress
SKU: HY-119968
Price: 620.00 USD
Availability: PreOrder

(Synonyms: Granaticin A; Litmomycin)

Granaticin A inhibits the initial stage of RNA biosynthesis, has anti-Gram-positive bacteria, Mycobacterium (weak) and Vaginal trichomonas activity, but also can inhibit tumor cells.

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CAS No.: 19879-06-2
Formule: C₂₂H₂₀O₁₀
Masse moléculaire:444.39

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Granaticin Chemical Structure

CAS No.: 19879-06-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Granaticin A inhibits the initial stage of RNA biosynthesis, has anti-Gram-positive bacteria, Mycobacterium (weak) and Vaginal trichomonas activity, but also can inhibit tumor cells^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	1.3 μM Compound: Granaticin A	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 25153802]
HCT-116	IC₅₀	11 μM Compound: Granaticin A	Cytotoxicity against human HCT116 cells by MTT assay Cytotoxicity against human HCT116 cells by MTT assay	[PMID: 25153802]
HeLa	IC₅₀	0.7 μM Compound: Granaticin A	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 25153802]
HepG2	IC₅₀	6.6 μM Compound: Granaticin A	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 25153802]

Chemical Information

CAS No. 19879-06-2
Masse moléculaire 444.39
Formule C₂₂H₂₀O₁₀
SMILES

O[C@@]12C3=C(O)C(C(C4=C([C@@]5([H])[C@@](CC(O5)=O)([H])O[C@H]4C)C6=O)=O)=C6C(O)=C3[C@@](O[C@@H]2C)([H])C[C@H]1O
Synonyms

Granaticin A; Litmomycin
Structure Classification
- Antibiotics
- Other Antibiotics
Initial Source
- Microorganism
Streptomyces sp. 166
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Qianqian Lv, et al. Sekgranaticin, a SEK34b-Granaticin Hybrid Polyketide from Streptomyces sp. 166. J Org Chem. 2019 Jul 19;84(14):9087-9092. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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