Inakalant
Inakalant is an atrial specific potassium channel blocker with antiarrhythmic activity. Inakalant works by selectively blocking potassium channels in heart cells, thereby prolongs the action potential duration (APD) of cardiomyocytes and increases the effective refractory period of the atria and ventricles, which helps to terminate and prevent the occurrence of arrhythmias such as atrial fibrillation (AF). Inakalant can be used in the study of arrhythmia and cardiac electrophysiology.
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- CAS No.: 335619-18-6
- Formule: C23H34N4O5
- Masse moléculaire:446.54
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
Chemical Information
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CAS No. 335619-18-6
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Masse moléculaire 446.54
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Formule C23H34N4O5
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SMILES
N#CC(C=C1)=CC=C1OC[C@@H](O)CN2CC3OC(CN(C3)CCNC(OC(C)(C)C)=O)C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Edvardsson N, et al. Inverse correlation between the atrial fibrillatory rate and the ventricular repolarization time: observations at baseline and after an intravenous infusion of a combined potassium and sodium current blocker[J]. Annals of Noninvasive Electrocardiology, 2016, 21(3): 236-245. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Inakalant Related Classifications
HY-14924 Related Classifications
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