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Cat. No.: HY-15499

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K-832

K-832 is an orally active IL-1β secretion inhibitor. K-832 can be used in the research of rheumatoid arthritis.

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CAS No.: 225666-85-3
Formule: C₂₄H₁₉ClN₂OS
Masse moléculaire:418.94

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

K-832 Chemical Structure

CAS No.: 225666-85-3

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
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Activité biologique

Description

K-832 is an orally active IL-1β secretion inhibitor. K-832 can be used in the research of rheumatoid arthritis^[1]^[2].

IC₅₀ & Target^[1]^[2]

IL-1β

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Chemical Information

CAS No. 225666-85-3
Masse moléculaire 418.94
Formule C₂₄H₁₉ClN₂OS
SMILES

O=C1C=C(C2=CC=C(Cl)C=C2)C(C3=CC=C(SC)C=C3)=NN1CC4=CC=CC=C4
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Dumont F J. The interleukin-1 families of cytokines and receptors: therapeutic potential for immunomodulation and the treatment of inflammatory disorders. Expert Opinion on Therapeutic Patents, 2006, 16(7): 879-912.

[2]. Halim S A, et al. Attempt to explore the binding mechanism of IL-1β inhibitors via molecular docking studies. Med. Chem, 2015, 5(10): 452-457.

Calculators

Calculateur de molarité

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Calculateur de dilution

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Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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K-832

Voir tous les produits spécifiques à Isoform Interleukin Related