LSD1-IN-49
LSD1-IN-49 is an irreversible LSD1/KDM1A inhibitor with an IC50 of 29 nM against hLSD1. LSD1-IN-49 irreversibly inhibits the enzymatic activity of LSD1 by forming an adduct with flavin adenine dinucleotide (FAD) in the binding pocket of LSD1. LSD1-IN-49 is applicable to research related to schizophrenia, autism spectrum disorder and Huntington's disease.
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- CAS No.: 1422533-70-7
- Formule: C26H26N2O
- Masse moléculaire:382.50
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
[1]|
LSD1 29 (hLSD1) nM (IC50) |
In Vitro
LSD1-IN-49 (Compound (±) 1) irreversibly inhibits the activity of recombinant hLSD1 enzyme, with an IC50 of 29 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1422533-70-7
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Masse moléculaire 382.50
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Formule C26H26N2O
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SMILES
O=C(C1=CC=C(C2=CC=CC=C2)C=C1)NC(C=C3)=CC=C3[C@H](C4)[C@@H]4NCC5CC5
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)