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Cat. No.: HY-186294

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Methyl-celastrol

Methyl-celastrol is a Celastrol (HY-13067) derivative and triterpenoid compound. Methyl-celastrol exists in Celastrus hypoleucus (Oliv) Warb f argutior Loes and other Celastraceae plants. Methyl-celastrol induces weight loss, reduces body fat, decreases food intake and improves glucose homeostasis. Methyl-celastrol is applicable to obesity-related research.

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CAS No.: 1810867-99-2
Formule: C₃₀H₄₀O₄
Masse moléculaire:464.64

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Please store the product under the recommended conditions in the Certificate of Analysis.

Methyl-celastrol Chemical Structure

CAS No.: 1810867-99-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
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Activité biologique

Description

In Vitro

Lipid Metabolism

Methyl-celastrol (Compound 18) induces weight loss, reduces body fat, decreases food intake, and improves glucose homeostasis in overweight and obese individuals^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Research Protocol for Metabolic Diseases

Chemical Information

CAS No. 1810867-99-2
Masse moléculaire 464.64
Formule C₃₀H₄₀O₄
SMILES

C[C@]12[C@@](C([C@@](CC1)3C)=CC=C(C(C)=C4OC)C3=CC4=O)(CC[C@@]5([C@@]2([H])C[C@@](C)(CC5)C(O)=O)C)C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Ralph Mazitschek, et al. Celastrol and derivatives for the treatment of obesity. WO2015148802A1. WIPO (PCT). 2015-03-26.

[2]. Yang H, et al. Targeting tumor proteasome with traditional Chinese medicine. Current drug discovery technologies. 2010 Mar;7(1):46-53. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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