MPI3
MPI3 is a reversible covalent SARS-CoV-2 MPro inhibitor with an enzymatic IC50 of 8.5 nM. MPI3 can be used for the research of covid-19.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 890648-84-7
- Formule: C26H38N4O6
- Masse moléculaire:502.60
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
In Vitro
MPI3 potently inhibits purified SARS-CoV-2 MPro with an enzymatic IC50 of 0.0085 μM[1].
MPI3 (72 h) shows weak cellular inhibition of SARS-CoV-2 MPro in transiently transfected HEK293T/17 cells, with a cellular IC50 greater than 2 μM[1].
MPI3 weakly inhibits SARS-CoV-2 replication in Vero E6 cells, with an antiviral EC50 greater than 5 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 890648-84-7
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Masse moléculaire 502.60
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Formule C26H38N4O6
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SMILES
O=C(NCC1)[C@@H]1C[C@@H](C=O)NC([C@H](CC(C)C)NC([C@H](C(C)C)NC(OCC2=CC=CC=C2)=O)=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)