Omodenbamab
Based on 1 Customer Validation
Omodenbamab is an anti-SpA (Staphylococcal protein A) human monoclonal antibody with a KD value of 0.0467 nM. Omodenbamab circumvents a key S. aureus evasion mechanism by targeting the cell wall moiety Protein A (SpA). Omodenbamab can be used in research of S. aureus bloodstream infection.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 96.77%
- CAS No.: 2241724-48-9
- Masse moléculaire:156.08 kDa
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Human IgG3 kappa
Human
staphylococcal protein A
Omodenbamab (514-G3) binds to S. aureus and leaves the Fc region exposed for FcγR1A receptor binding[1]. Omodenbamab (10 μg/mL; 30 min, 1.5 hr, and 2.5 hr) supports the opsonophagocytic killing of S. aureus by human blood cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Balb/C mice with MRSA in a bacteremia model[1]
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Dosage:2.5 mg/mice and 10 mg/mice
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Administration:Intravenous injection
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Result:Increased mouse Balb/C mice with MRSA in a bacteremia model survival.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Human IgG3 kappa
ELISA, FACS, Functional assay
Chemical Information
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CAS No. 2241724-48-9
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Appearance Liquid
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Masse moléculaire 156.08 kDa
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Color Colorless to light yellow
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SMILES
[Omodenbamab]
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Synonyms
514-G3
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Livraison
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
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Fiche technique (259 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Omodenbamab Related Classifications
HY-P99770 Related Classifications
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