PD 165929
PD 165929 is a high affinity and competitive non-peptide neuromedin-B (NMB) receptor selective antagonist (Ki: 6.3 nM; IC50: 150 nM for rat NMB receptor).
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 185215-75-2
- Formule: C37H47N5O2
- Masse moléculaire:593.80
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
0.35 μM
Compound: 1
|
Affinity of [125I][D-Tyr0]-NMB to human Neuromedin B receptor expressed in HEK293 cells
Affinity of [125I][D-Tyr0]-NMB to human Neuromedin B receptor expressed in HEK293 cells
|
[PMID: 15149640] |
Chemical Information
-
CAS No. 185215-75-2
-
Masse moléculaire 593.80
-
Formule C37H47N5O2
-
SMILES
CC(C)C(C=CC=C1C(C)C)=C1NC(N[C@](CC2=CNC3=CC=CC=C23)(C)C(NCC4(C5=CC=CC=N5)CCCCC4)=O)=O
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)