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Cat. No.: HY-160246

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QL47B

QL47B, a biotinylated analogue of QL47 (HY-80003), is a potent inhibitor of BTK, with an IC₅₀ value of 1.3 μM. QL47B has anti-tumor activity.

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CAS No.: 1579278-92-4
Formule: C₄₆H₅₅N₉O₇S
Masse moléculaire:878.05

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

QL47B Chemical Structure

CAS No.: 1579278-92-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

QL47B, a biotinylated analogue of QL47 (HY-80003), is a potent inhibitor of BTK, with an IC₅₀ value of 1.3 μM. QL47B has anti-tumor activity^[1].

Chemical Information

CAS No. 1579278-92-4
Masse moléculaire 878.05
Formule C₄₆H₅₅N₉O₇S
SMILES

O=C1N(C2=C(C=C1)C=NC3=CC=C(C4=CN(C)N=C4)C=C32)C5=CC=C6C(N(C(/C=C/CNCCOCCOCCOCCNC(CCCC[C@H]7[C@](NC(N8)=O)([H])[C@]8([H])CS7)=O)=O)CC6)=C5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Hong Wu, et al. Discovery of a Potent, Covalent BTK Inhibitor for B‑Cell Lymphoma. ACS Chem Biol. 2014 May 16;9(5):1086-91. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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