(R)-MDL-101146
(R)-MDL-101146 is the R-isomer of MDL-101146. MDL-101146 is an orally active, competitive and reversible inhibitor against human neutrophil elastase (HNE) with a Ki value of 25 nM. MDL-101146 inhibits HNE-induced hemorrhage in hamsters. MDL-101146 is promising for research of emphysema, rheumatoid arthritis, chronic bronchitis, cystic fibrosis, adult respiratory distress syndrome and glomerulonephritis.
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- CAS No.: 163660-53-5
- Formule: C29H37F5N4O6
- Masse moléculaire:632.62
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Chemical Information
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CAS No. 163660-53-5
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Masse moléculaire 632.62
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Formule C29H37F5N4O6
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SMILES
CC(C)[C@@H](C(N1[C@H](C(N[C@H](C(C)C)C(C(C(F)(F)F)(F)F)=O)=O)CCC1)=O)NC(C2=CC=C(C(N3CCOCC3)=O)C=C2)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(R)-MDL-101146 Related Classifications
HY-120039 Related Classifications
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