Rhamnitol
Rhamnitol is the reduction product of L-rhamnose that can be found in the metabolism of ingested rhamnose in the body. Rhamnitol is promising for research of intestinal permeability assessment and carbohydrate metabolism.
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- CAS No.: 1114-16-5
- Formule: C6H14O5
- Masse moléculaire:166.17
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Chemical Information
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CAS No. 1114-16-5
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Masse moléculaire 166.17
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Formule C6H14O5
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SMILES
C[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Transepithelial/transendothelial electrical resistance assay
TEER measures electrical resistance across epithelial or endothelial monolayers cultured on permeable supports, and the readout reflects ionic conductance through the cell barrier, especially the paracellular pathway regulated by junctional integrity. TEER can be measured without destroying the monolayer and is commonly used before or during transport, permeability, barrier-disruption, and barrier-maturation experiments. TEER values are influenced by biological maturation and technical conditions; reported factors include temperature, medium formulation, passage number, electrode geometry, membrane properties, and junctional length during early monolayer maturation. Therefore, TEER should be interpreted with blank-insert subtraction, area normalization, repeated readings, and, when possible, orthogonal barrier readouts such as FITC-dextran flux or tight-junction staining.
Pureté et documentation
Références
[1]. Wang TL, et al. Comprehensive analysis of natural polysaccharides from TCMs: a generic approach based on UPLC-MS/MS. Carbohydr Polym. 2022 Feb 1;277:118877. [Content Brief]
[2]. Malagon I, et al. Rhamnose and rhamnitol in dual sugar permeability tests. J Pediatr Gastroenterol Nutr. 2006 Aug;43(2):265-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)