RO5464466
RO5464466 is an hemagglutinin (HA) inhibitor of influenza H1N1 viruses. RO5464466 inhibits HA-mediated hemolysis of chicken erythrocytes with the IC50 of 0.29 μM.
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- CAS No.: 1399767-47-5
- Formule: C16H26N2O3S
- Masse moléculaire:326.45
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDCK | CC50 |
>100 μM
Compound: 28
|
Cytotoxicity against MDCK cells after 3 days by MTT assay
Cytotoxicity against MDCK cells after 3 days by MTT assay
|
[PMID: 24900355] |
| MDCK | EC50 |
0.21 μM
Compound: 28
|
Antiviral activity against Influenza A virus (A/Weiss/1943(H1N1)) infected in MDCK cells assessed as inhibition of virus-induced cytopathic effects after 3 days by MTT assay
Antiviral activity against Influenza A virus (A/Weiss/1943(H1N1)) infected in MDCK cells assessed as inhibition of virus-induced cytopathic effects after 3 days by MTT assay
|
[PMID: 24900355] |
Chemical Information
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CAS No. 1399767-47-5
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Masse moléculaire 326.45
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Formule C16H26N2O3S
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SMILES
O=S(C1=CC=CC(NC[C@]2(C)CC(C)(C)C[C@H](O)C2)=C1)(N)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)