ST80
ST80 is an inhibitor for interaction of OTUD4 and CD73. ST80 decreases CD73 protein level, increases CD73 protein turnover, reduces immune evasion of tumor cells, and thus exhibits antitumor efficacy against immunosuppressive triple-negative breast cancer (TNBC).
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- CAS No.: 3080717-78-5
- Formule: C26H24FN5O2
- Masse moléculaire:457.50
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
Chemical Information
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CAS No. 3080717-78-5
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Masse moléculaire 457.50
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Formule C26H24FN5O2
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SMILES
O=C1N(C2=NN([C@@H](C3=CC=C(F)C=C3)C[C@@H](C4=CC=C(C)C=C4)N5)C5=N2)C([C@@]6([H])CC=CC[C@]61[H])=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Hot Topics
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Topics
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Topics Process of PD-1/PD-L1-Mediated Tumor Immune Evasion
PD-1/PD-L1-mediated tumor immune evasion is a central mechanism by which tumors suppress antitumor immunity through immune checkpoint signaling.
2026-06-18
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Topics Escape Route Built by TGF-β Signaling
Escape route built by TGF-β signaling refers to the immunosuppressive and stromal remodeling program through which tumors avoid immune elimination and reduce response to cancer immunotherapy.
2026-06-18
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ST80 Related Classifications
HY-161774 Related Classifications
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